Creation of monosodium iodoacetate-induced model of osteoarthritis in rabbit knee joint
نویسندگان
چکیده
منابع مشابه
Long-term histopathological developments in knee-joint components in a rat model of osteoarthritis induced by monosodium iodoacetate
[Purpose] This study was performed to evaluate the long-term histopathological changes in knee-joint components including synovial membrane and joint capsule in a rat model of osteoarthritis (OA) induced by monosodium iodoacetate (MIA). [Subjects and Methods] Fifty male rats were used. OA was induced through intra-articular injection of MIA, and ten rats were randomly allocated to each of five ...
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PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes of the synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in the joint and corresponded to the control group. The second was submitted to experimental osteoarthritis of the right knee induced by monosodium i...
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Osteoarthritis (OA) is characterized by a progressive degradation of cartilage and loss of joint function. A simple and reproducible animal model that mimics molecular and pathological changes in the articular cartilage of knee joint OA would help in understanding its pathophysiological mechanism and aid in the preclinical assessment of disease modifying drugs. The aim of our study is to evalua...
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Ganghwaljetongyeum is a traditional Korean herbal medicine used to treat joint pain, limited motion, fever, and swelling; it also inhibits inflammatory processes associated with arthritis. ChondroT, a water extract of Ganghwaljetongyeum, is a new complex herbal medicine. This study investigated the effects of ChondroT using a rat model of monosodium iodoacetate- (MIA-) induced osteoarthritis. T...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Research
سال: 2018
ISSN: 0971-5916
DOI: 10.4103/ijmr.ijmr_2004_16